Clinical biochemical study on the behavior of prostate-specific antigen in individuals of different age groups exposed to organophosphates and carbamates

Authors

  • José Moreno-Serrano Facultad Agropecuaria y de Recursos Naturales Renovables, Universidad Nacional de Loja, Loja, Ecuador
  • Edwin Caraguay Chamba Ministerio de Salud, Santa Elena, Ecuador.
  • Ana Judith Eras Curimilma Ministerio de Salud, Loja, Ecuador

Abstract

Prostate alterations are one of the most common problems that affect men over 40 years old, being the most frequent: benign prostatic hyperplasia, prostatitis, prostate cancer, etc. Thus, the determination of the prostate specific antigen (PSA) is currently a screening test for prostate cancer and prostate abnormalities. The present study is a descriptive cross-sectional observational design, where 60 male individuals were included, aged between 40 and 70, who have been exposed for years to pesticides (organophosphorated and carbamates). The measurement of PSA concentration was determined with the ECLIA method (electrochemiluminescence immunoassay). Total PSA values (>4.0 ng / ml) and free PSA (>0.90 ng/ml) and free/total PSA values (<25 %) were obtained after 50 years of age. It was established in this study that the increase in the value of PSA early in 50-year-old men could be directly related to farmers’ exposure to organophosphated and carbamates.

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Published

2019-12-31

How to Cite

Moreno-Serrano, J. ., Caraguay Chamba, E., & Eras Curimilma, A. J. . (2019). Clinical biochemical study on the behavior of prostate-specific antigen in individuals of different age groups exposed to organophosphates and carbamates. CEDAMAZ, 9(2), 53–57. Retrieved from https://revistas.unl.edu.ec/index.php/cedamaz/article/view/883

Issue

Vol. 9 No. 2 (2019): CEDAMAZ

Section

Research Articles

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